Rapid Chemical Profiling of Compound Huanggen Granules and Absorbed Prototypes in Cynomolgus Monkey Plasma by Integrating UHPLC-Q-TOF-MS E Method and Data Post-Processing Strategy.

Current drug metabolism(2022)

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摘要
It was demonstrated that the data post-processing strategy applied in this study could greatly simplify the data post-processing process and enhance the structural identification efficiency by reducing the possibility of false positives, and the results obtained might be helpful for further studies on the quality control, pharmacokinetics and pharmacodynamics of CHG.
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关键词
CHG,UHPLC-Q-TOF-MS,chemical profiling,cynomolgus monkey,integrated strategy,prototypical components
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