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Efficacy and Safety of Low-Dose Brexpiprazole for Acute Schizophrenia: Meta-Analysis of Randomized Placebo-Controlled Trials.

Mingjun Zhao,Bin Qin,Yage Mao,Hailing Wang,Aiqin Wang,Chuansheng Wang

Neuropsychiatric disease and treatment（2022）

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Abstract
The results indicated that low-dose brexpiprazole may be not superior for improving the efficacy and safety for acute schizophrenia compared to placebo and standard-dose brexpiprazole, and may cause additional risk of increasing body weight. Therefore, using low-dose brexpiprazole in acute schizophrenia patients may be not recommended.
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Key words
RCTs,acute schizophrenia,brexpiprazole,meta-analysis,placebo
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