Inflammation and Metabolism of Influenza-Stimulated Peripheral Blood Mononuclear Cells From Adults With Obesity Following Bariatric Surgery.

William D Green,Yazan Alwarawrah,Abrar E Al-Shaer,Qing Shi,Michael Armstrong,Jonathan Manke,Nichole Reisdorph,Timothy M Farrell,Steven D Hursting,Nancie J MacIver,Melinda A Beck,Saame Raza Shaikh

The Journal of infectious diseases（2022）

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摘要

These results show that obesity drives a signature of impaired PBMC metabolism, which may be due to persistent inflammation. PBMC metabolism was not reversed after short-term weight loss despite improvements in measures of systemic metabolism.

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关键词

bariatric surgery,immunometabolism,inflammation,influenza virus

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