Molecular Interactions of Zyesami with the SARS-CoV-2 nsp10/nsp16 Protein Complex.

Sultan F Alnomasy,Bader S Alotaibi, Ziyad M Aldosari,Ahmed H Mujamammi,Ahmad Alzamami,Pragya Anand,Yusuf Akhter,Farhan R Khan,Mohammad R Hasan

Combinatorial chemistry & high throughput screening（2023）

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摘要

The structural bioinformatics analyses have indicated the potential binding specificity of Zyesami and nsp16. Data predict how the initial binding of Zyesami with nsp10 and nsp16 may occur. Moreover, this binding could significantly inhibit the 2 -O-MTase activity of the SARSCoV nsp10/16 complex.

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关键词

COVID-19,SARS-CoV-2,coronavirus,microbiology,nsp10,nsp16,zyesami

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