Epigenetic Age Acceleration Markers Are Associated With Physiologic Frailty and All-Cause Mortality in People With Human Immunodeficiency Virus.

Krisann K Oursler,Vincent C Marconi,Zeyuan Wang,Ke Xu,Monty Montano,Kaku So-Armah,Amy C Justice,Yan V Sun

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

The observed associations between EAA markers with physiologic frailty and mortality support future research to provide mechanistic insight into the accelerated aging process and inform interventions tailored to PWH for promoting increased healthspan.

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DNA methylation,aging,epigenetics,frailty,mortality

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