Antiphospholipid antibodies in patients with calcific aortic valve stenosis.

Oscar Plunde,Elisabet Svenungsson,Giulia Ferrannini,Anders Franco-Cereceda,Magnus Bäck

Rheumatology (Oxford, England)（2023）

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摘要

aPL IgG was more common in CAVS patients compared with matched controls and aPL positivity was associated with altered AV transcriptomics related to local disease progression and interferon pathways. Further studies should aim to establish aPL as a possible risk marker and/or causal factor for CAVS and could offer new precision therapeutic targets.

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关键词

SLE,aPL,antiphospholipid syndrome,calcific aortic valve stenosis,heart valve disease,transcriptomics

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