Interaction between adipoderivated mesenchymal stem cells and PLGA/PIepox scaffold with possible use in tissue engineering: in vitro study

The objective of this work was to evaluate the interaction between human mesenchymal cells adipoderived with PLGA/PIepox scaffold made by the centrifugation technique. The best plating cell density was predicted between 0.32 x 10(5), 0.65 x 10(5) and 1.3 x 10(5) and the best culture time between 24, 48, 72 h. The metabolic activity of the tested groups was similar to their respective controls, except for the higher density and longer cultivation time, which were metabolically more active. The association between the PLGA/PIepox scaffold and adipoderived mesenchymal cells can be considered for future in vivo studies in tissue engineering.