Rate Of Helicobacter pylori Antigen Detection In Relation To Laboratory Criteria Among Adult Patients With Acute Gastroenteritis

Gastroenteritis are one of the social problems in developing countries. The pathogens commonly associated with Patients are Salmonella, Clostridium difficile, Shigella, Yersinia, Escherichia coli and H.pylori. The aim of the study was to evaluate the presence of H.pylori antigen in acute gastroenteritis in adult patients in relation to other laboratory criteria. The study was performed on freshly collected stool samples among 118 acute gastroenteritis patients admitted to two teaching hospitals from May 2017 to January 2018. A questionnaire was completed for each patient name, age, gender, clinical data like fever, nausea, Vomiting, abdominal pain. The criteria included hemorrhagic fresh stool sample in addition to containing parasites agent. Fresh stool samples were tested by Immunochromatographic assay for antigenic detection of H.pylori. a blood samples was taken from each patients as well as other(30) healthy control matching in age and gender. The study included measurement the concentration of Interleukin-8, serum amylase activity in sera of patients and control. H.pylori antigen identified in 35 stool samples 16 for females and 19 samples for males. most patients show fever, vomiting and abdominal pain, stool samples show 100 % without blood, 84.74 % with pus, 10.16 % with mucous. presence of Entamoeba histolytica and Giardia lamblia cyst. The percent was 15.25% and 7.63% respectively. also, The result indicated. The concentration of IL-8, increased significantly while the serum amylase activity decreased significantly in both interval ages in patients sera in comparison with healthy control. H.pylori Antigen present in 35 stool samples out of 118 cases most the patients show vomiting, fever, abdominal pain, all the cases without blood,100 cases with pus. 16 cases with mucous, 9 cases with G.lamblia and 18 cases with cyst of E.histolytica. The concentration of IL-8increased significantly while the serum amylase activity decreased significantly in both interval ages in patients sera in comparison with healthy control.