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In Situ Decoration of TiO2 Nanowire Microspheres with Silk Fibroin for Enhanced Biocompatibility

Cunfang Zhang,Xinyan Zhang,Song Chen,Jianan Zhang,Shuaishuai Li,Xiaona Li,Toshiyuki Ikoma,Weiyi Chen

Materials letters（2022）

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Abstract
Novel silk fibroin-decorated TiO2 nanowire microspheres were synthesized through in situ decoration of TiO2 nanowire microspheres with silk fibroin. They exhibited a hierarchical and fibrous structure with a diameter of 400-500 mu m and consisted of numerous nanowires with the diameter of 10-20 nm. After incubation with fibroblast L929 cells, they showed an enhanced biocompatibility due to the presence of silk fibroin in contrast to TiO2 nanowire microspheres.
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Biomaterials,Composite materials,Microstructure
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