Magnesium Level in the Mortality Prediction of Community-acquired Pneumonia Patients

MEANDROS MEDICAL AND DENTAL JOURNAL(2022)

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摘要
Objective: We aimed to examine the contribution of pneumonia severity index and blood magnesium (Mg) level of community-acquired pneumonia (CAP) patients who received inpatient treatment in our hospital to the mortality of the cases. Materials and Methods: Our study is a retrospective study in which we applied to the emergency department (ED) of our hospital in 2018, with the diagnosis of CAP, and were hospitalized to the wards or intensive care unit (ICU). Results: A total of 279 patients with CAP were enrolled in this study. All-cause mortality on the 28th day of follow-up was 13.6%. There were statistically significant results between the 2 groups (survivors and non-survivors), which were classified based on their 28-day mortality rates, in terms of the Mg, pneumonia severity index (PSI), and confusion, urea, respiratory rate, blood pressure, age >65 years (CURB-65) values. Moreover, the optimal Mg cut-off for predicting 28-day mortality at the time of ED admission was determined to be 1.90 mg/dL, with 71% sensitivity, 73% specificity, and 73% accuracy. ROC analysis revealed that the areas of Mg under the AUC in terms of 28-day mortality were 0.778. Thirty-eight patients died during the first 28-day period. Of these, 27 (64,2 0 10) had Mg level <1.90 mg/dL. Independent predictors of 28-day mortality rates were determined to be Mg (lower than 1.90 mg/dL), CURB-65, PSI, vasopressor need and stay ICU. Conclusion: Mortality rates increase as the Mg level decreases in CAP patients.
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关键词
Community-acquired pneumonia, magnesium level, mortality, emergency medicine
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