A chronotherapeutic study of Shalaparni Ksheerapaka in prehypertension

Prehypertension is one of the major health concerns and has shown increasing epidemiology globally. The treatment of prehypertension using a safer and tolerable strategy, thus becomes a pressing priority. The purpose of the study was to evaluate the effect of Shalaparni Ksheerapaka based on chronotherapy in individuals as a treatment of prehypertension. Sixty patients were randomly allocated into three different groups according to the time of oral drug administration. All the patients performed the trial session for 30 days. Assessment of the results was done on the basis of pre-decided subjective (feeling of headache, dizziness and fatigue) and objective parameters (systolic and diastolic blood pressure) before and after the treatment. After 30 days of therapy, BP was normalized significantly with systolic BP as 123.1 +/- 3.14 and diastolic BP as 81.2 +/- 2.09 when Shalaparni Ksheerapaka was administered post lunch, i.e., vyana vayu kala. Likewise, a significant improvement in subjective parameters of prehypertension was evident in groups that received Shalaparni Ksheerapaka post lunch and dinner. The present article emphasizes on the therapeutic value of Shalaparni in the treatment and control of prehypertension and unfolds the potential of Shalaparni Ksheerapaka as a promising drug for treatment of various other diseases.