Molecular cages encapsulating lipase and the effect of cage hydrophobicity and cage size

Meng-Dan Gong,Xin-Jiang Pei, Guang-Xu Duan,Gao-Ying Zhi,Zhi-Qin Liu,Dong-Hao Zhang

Materials & Design（2022）

引用 3|浏览5

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摘要

•Molecular cage encapsulation protects lipase activity from covalent binding.•The optimum cage hydrophobicity (logP = 1.26) is determined.•The optimum cage size (4.70 nm) is determined.•Molecular docking revealed the interaction of lipase with molecular cage.

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关键词

Nano-molecular cage,Cage hydrophobicity,Cage size,Lipase encapsulation,Active conformation,Stability

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