Online-learning-aided optimization and interpretation of sugar production from oil palm mesocarp fibers with analytics for industrial applications

•A new online learning framework was developed for optimizing sugar production (SP)•Efficacy of SP from biomass was significantly improved by model-guided experiments•Impacts of experimental conditions and their interactions on SP were well explored•Generic modelling framework was provided for biomass valorization related researchers•Potential implication analysis has shown valuable insights for future industrialization