Cardiopulmonary Toxicity Following Intensity-Modulated Proton Therapy (IMPT) Versus Intensity-Modulated Radiation Therapy (IMRT) for Stage III Non-Small Cell Lung Cancer.

Nathan Y Yu,Todd A DeWees,Molly M Voss,William G Breen,Jennifer S Chiang,Julia X Ding,Thomas B Daniels,Dawn Owen,Kenneth R Olivier,Yolanda I Garces,Sean S Park,Jann N Sarkaria,Ping Yang,Panayiotis S Savvides,Vinicius Ernani,Wei Liu,Steven E Schild,Kenneth W Merrell,Terence T Sio

Clinical Lung Cancer（2022）

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摘要

IMPT is associated with a reduced risk of clinically significant pneumonitis and cardiac events when compared with IMRT without compromising tumor control in stage III NSCLC. IMPT may provide a safer treatment option, particularly for high-risk patients with poor pretreatment pulmonary function.

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关键词

Cardiopulmonary Toxicity,Intensity-Modulated Proton Therapy,Intensity-Modulated Radiation Therapy,Locally Advanced Lung Cancer,Non-Small Cell Lung Cancer

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