Systematic identification of molecular mechanisms for aryl hydrocarbon receptor mediated neuroblastoma cell migration

•Low concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin could induce the directional migration of human neuroblastoma cells.•The upregulated genes were significantly enriched in the cell migration-related biological pathways.•The AhR-mediated mRNA and miR expressions involved in the axon guidance pathway played an important role.•The putative dioxin-responsive elements were present in the promoter regions of most genes and miRs in the axon guidance pathway.