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Mast cells and tryptase are linked to itch and disease severity in mycosis fungoides: Results of a pilot study.

Dorothea Terhorst-Molawi, Katharina Lohse,Katharina Ginter,Viktoria Puhl,Martin Metz,Man Hu,Marcus Maurer,Sabine Altrichter

Frontiers in Immunology（2022）

Cited 3|Views4
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Abstract
The MC-mediator tryptase, in MF, is linked to disease activity and impact, most prominently to itch. Our findings call for larger studies that explore the role of MCs, tryptase and other MC mediators as drivers of itch and their role in MF pathogenesis.
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Key words
cutaneous T-cell lymphoma,eosinophil,itch (pruritus),mast cell,mycosis fungoides,tryptase
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