3D high resolution clonogenic survival measurement of xrs-5 cells in low-dose region of carbon ion plans.
International journal of radiation biology(2023)
Abstract
We conclude that the V-bottom 384-well plates in combination with the radiation-sensitive xrs-5 cell line constitute a suitable radiobiological verification tool which can be used especially for low doses. Furthermore, the measured survival of xrs-5 cells show a good agreement with the expected survival in the low-dose out-of-field regions, both laterally and downstream of the target.
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Key words
3D cell culture in ECM,biological treatment plan verification,carbon ion beam therapy,xrs-5 cells
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