Effects of Ketamine Infusion on Breathing and Encephalography in Spontaneously Breathing ICU Patients.

Aiman Suleiman,Peter Santer,Ronny Munoz-Acuna,Maximilian Hammer,Maximilian S Schaefer,Luca J Wachtendorf,Sandra Rumyantsev,Lorenzo Berra,Shubham Chamadia, Oluwaseun Johnson-Akeju,Elias N Baedorf-Kassis,Matthias Eikermann

Journal of intensive care medicine（2023）

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摘要

In intubated, spontaneously breathing patients receiving a constant rate of propofol, ketamine increased inspiratory flow, reduced inspiratory work of breathing, and was associated with an "activated" electroencephalographic pattern. These characteristics might facilitate weaning from mechanical ventilation.

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关键词

ICU sedation,Ketamine infusion,brain activity,critical care ventilation,inspiratory flow,mechanical ventilation,spontaneous breathing trial,weaning from ventilator

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