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Severe Radiation-Induced Lymphopenia Attenuates the Benefit of Durvalumab After Concurrent Chemoradiotherapy for NSCLC

Wang Jing,Ting Xu,Lirong Wu, Pablo B Lopez,Clemens Grassberger,Susannah G Ellsworth,Radhe Mohan,Brian P Hobbs,George R Blumenschein,Janet Tu,Mehmet Altan,Percy Lee,Zhongxing Liao,Steven H Lin

JTO Clinical and Research Reports（2022）

Cited 9|Views5
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Abstract
Severe RIL compromises survival benefits from durvalumab after CCRT for NSCLC. Measures to mitigate RIL after CCRT may be warranted to enhance the benefit of consolidation durvalumab.
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Key words
NSCLC,Lymphopenia,Radiation,Immunotherapy,Durvalumab,Consolidative therapy
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