Hyperimmune Globulin for Severely Immunocompromised Patients Hospitalized With Coronavirus Disease 2019: A Randomized, Controlled Trial.

Sammy Huygens,Quincy Hofsink,Inger S Nijhof,Abraham Goorhuis,Arnon P Kater,Peter A W Te Boekhorst,Francis Swaneveld,Věra M J Novotný,Susanne Bogers, Matthijs R A Welkers,Grigorios Papageorgiou,Bart J Rijnders,Jarom Heijmans

The Journal of infectious diseases（2023）

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摘要

Antisevere acute respiratory syndrome coronavirus 2 hyperimmune globulin may be a valuable treatment in severely immunocompromised, hospitalized, COVID-19 patients and should be considered when no monoclonal antibody therapies are available.

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关键词

B-cell dysfunction,COVID-19,anti-SARS-CoV-2 hyperimmune globulin,plasma-derived antibody therapy,severely immunocompromised state

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