HNF4A Defines Molecular Subtypes and Vulnerability to TGFβ-pathway Targeted Therapies in Cancers of the Distal Esophagus.

Andrew E Blum,Durgadevi Ravillah,Ramachandra M Katabathula,Sirvan Khalighi,Vinay Varadan, Kishore Guda,Salendra Singh,Yanling Miao,Adam M Kresak,Joseph E Willis,Marcia I Canto,Jean S Wang,Nicholas J Shaheen,Amitabh Chak

Gastroenterology（2022）

Cited 3|Views17

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Key words

Barrett adenocarcinoma,Barrett neoplasia,CW1474,Cancer therapy,ERBB2,ESO26,EW-7197,EsoAd1,Esophagus cancer,FLO-1,HNF4,OE19,P53,SKGT4,Smad4,TEW-7197,TNFAIP3,Vactosertib,biomarker,cancer subtypes,hepatic nuclear factor,nuclear receptor,patient derived xenograft,transforming growth factor,xenograft

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