Impact of a Laboratory-Developed Phenotypic Rapid Susceptibility Test Directly From Positive Blood Cultures on Time to Narrowest Effective Therapy in Patients With Gram-Negative Bacteremia: A Prospective Randomized Trial.

Alyssa B Christensen,Brent Footer,Tobias Pusch,Kim Heath, Maha Iqbal, Lian Wang,Gregory Tallman, Cameron Cover, Jennifer Marfori,Brian Kendall,Nick Stucky, Meagan Greckel, Ivor L Thomas, Katelynn Tran, Salena Yip,Margret Oethinger

Open forum infectious diseases（2022）

引用 3|浏览5

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摘要

In patients with GN-BSI, rAST did not significantly decrease time to narrowest effective therapy but did decrease time to oral antibiotics and length of hospital stay. Rapid AST using existing microbiology platforms has potential to optimize patient outcomes.

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关键词

antimicrobial stewardship,antimicrobial susceptibility testing,bloodstream infection,gram negative,rapid diagnostic testing

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