Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice.

Garazi Pena Alzua,Anne Finne Pihl,Anna Offersgaard,Carlos Rene Duarte Hernandez, Zhe Duan,Shan Feng,Ulrik Fahnøe,Christina Sølund,Nina Weis,Mansun Law,Jannick C Prentoe,Jan Pravsgaard Christensen, Jens Bukh,Judith Margarete Gottwein

Gut（2023）

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摘要

High-yield genotype 1-3 HCV could be developed as basis for inactivated vaccine candidates inducing broadly neutralising antibodies in mice supporting further preclinical development.

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关键词

HCV,chronic viral hepatitis,hepatitis C,immune response,molecular biology

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