Effects of RETN polymorphisms on treatment response in rheumatoid arthritis patients receiving TNF-α inhibitors and utilization of machine-learning algorithms
International Immunopharmacology(2022)
摘要
•The resistin gene was positively correlated with tumor necrosis factor-alpha.•rs3219177 polymorphism and male sex were positively associated with the treatment.•This study trained various prediction models and provided insights into treatment.
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关键词
Arthritis,Rheumatoid,Tumor necrosis factor-alpha,Resistin,RETN,Machine learning,Polymorphism
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