Biological features of TcM: A new Trypanosoma cruzi isolate from Argentina classified into TcV lineage

Santiago José Martinez,Gonzalo Nicolás Nardella,Matías Exequiel Rodríguez,Cynthia Vanesa Rivero,Fernán Agüero,Patricia Silvia Romano

Current Research in Microbial Sciences（2022）

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摘要

•TcM is a new T. cruzi isolate that belongs to DTU TcV.•TcV is a T. cruzi linage prevalent in human infections of Argentina.•TcM is less virulent that TcY strain.•TcM displays slow-growing rate and muscle tissue tropism.•TcM is more susceptible to benznidazole than TcY.

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关键词

Trypanosoma cruzi,DTUs,Tissue tropism,Chronic strain,Drug susceptibility

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