A Lentiviral Vector Encoding Fusion of Light Invariant Chain and Mycobacterial Antigens Induces Protective CD4+ T Cell Immunity.

Jodie Lopez,Francois Anna,Pierre Authie,Alexandre Pawlik,Min-Wen Ku,Catherine Blanc,Philippe Souque,Fanny Moncoq,Amandine Noirat,David Hardy,Wladimir Sougakoff,Roland Brosch,Francoise Guinet,Pierre Charneau,Laleh Majlessi

Cell Reports（2022）

引用 9|浏览30

关键词

lentiviral vectors,MHC-II antigenic presentation,CD4+ T cell response,intranasal immunization,mucosal immunity,tuberculosis,mycobacteria,polyantigen,antigen routing,polyfunctional T cells

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