IGF2BP2 promotes pancreatic carcinoma progression by enhancing the stability of B3GNT6 mRNA via m6A methylation.
Cancer medicine(2023)
Abstract
Elevated m6A levels promote PC progression. IGF2BP2 is a credible marker and modulates B3GNT6 mRNA stability, indicating that IGF2BP2 is a potential prognostic marker and therapeutic target in PC progression.
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Key words
B3GNT6,IGF2BP2,RNA methylation,epigenetic modification,pancreatic carcinoma
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