Optical Techniques for Treatment and Tissue Evaluation Using Skin Models for Preclinical Studies

Handbook of Animal Models and its Uses in Cancer Research(2023)

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Abstract
Cancer is one of the most incident diseases in the world, and skin cancer is the most prevalent type, making it a public health problem. New treatments and optimization of existent protocols are always desired to prolong or improve human life. The better way to avoid complications for patients with skin cancer is by providing efficient diagnosis and accessible treatment. For this purpose, it is indispensable to perform preclinical trials for the new therapies’ developments and new diagnosis methods. The standardization of skin tumor models in animals and the techniques to explore treatment response is what can make the translational to humans quicker. This chapter summarizes the main different animal models including chorioallantoic membrane and skin lesions induction procedures in this research area as well as the techniques to evaluate and monitor the treatment’s efficiency and optical techniques that help the diagnosis and understanding of biological samples.
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