Noninvasive OCTA-based blood glucometry
Dynamics and Fluctuations in Biomedical Photonics XIX(2022)
摘要
We investigated the correlation of the blood optical attenuation coefficient (OAC) and the blood glucose concentration (BGC). The blood OAC was measured in mouse retina in vivo through OCT angiography (OCTA). The arteries and veins presented a blood OAC change of ~0.05-0.07 mm-1 per 10 mg/dl and a significant elevation of blood OAC in diabetic mice was observed. Besides, the veins had a higher correlation coefficient between the measured blood OAC and BGC than that of the arteries. The blood OAC-BGC correlation suggests a concept of non-invasive OCTA-based glucometry, allowing a fast assessment of the blood glucose of specific vessels.
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关键词
Cerebral Blood Flow Measurement,Brain Oxygenation Monitoring,Optical Coherence Tomography Angiography,OCT Technology,Optical Coherence Tomography
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