靶向肠道菌群清除硫酸吲哚酚的研究现状
Journal of Clinical Nephrology（2022）
Abstract
硫酸吲哚酚(indoxyl sulfate,IS)作为一种典型的经肠道微生物代谢的尿毒症毒素,在慢性肾脏病(chronic kidney disease,CKD)及其相关并发症的发生、发展中起到重要作用.随着"肠肾轴"理论的提出,表明CKD患者在发生肠道菌群失调的同时,也会导致IS水平的升高,进一步加快CKD的进程,预后不佳.本文就近几年通过靶向肠道菌群清除IS的方法作一综述.
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