Skeletal muscle deconditioning during partial weight-bearing in rodents – A systematic review and meta-analysis

•Partial weight-bearing in rodents has been employed as a hypogravity analogue.•Loading at 20%, 40%, and 70% of full body weight causes muscular deconditioning.•Deconditioning often occurred in a dose-response manner with the level of loading.•The patterns of deconditioning resembled those that occur during complete unloading.