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Changes in brain response to urgency before and after treatment of urgency urinary incontinence with onabotulinumtoxin A.

Becky D Clarkson,Helmet T Karim,Christopher J Chermansky,Layla Banihashemi,Shachi Tyagi,Derek J Griffiths,Neil M Resnick

Neurourology and urodynamics（2022）

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Abstract
The changes seen in the brain control mechanism after therapy likely reflect reduced bladder sensation caused by BoNTA's peripheral action. We ascribe the SMG and IFG changes to a coping mechanism for urgency which is reduced in those who respond well to treatment.
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Key words
OAB,bladder control,brain,onbotulinumtoxin A,urgency urinary incontinence
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