RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child

Rongfeng Qi,Zhihong Cao,Wesley Surento,Li Zhang,Lianli Qiu, Zhuoman Xia,Christopher R.K. Ching,Qiang Xu,Yan Yin,Long Jiang Zhang,Lingjiang Li,Yifeng Luo,Guang Ming Lu

Journal of Affective Disorders（2022）

引用 4|浏览11

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摘要

•The RORA gene polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness•Within RORA T/T genogroup, greater PTSD symptom severity was correlated with thicker transverse temporal gyrus (bilateral)•Within RORA G/T genogroup, greater PTSD symptom severity was correlated with reduced thickness of transverse temporal gyrus

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关键词

RORA,Loss of an only child,Post-traumatic stress disorder,Cortical thickness,Subcortical volume,Moderation effect

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