Mesenchymal stem cells and prostate cancer: A concise review of therapeutic potentials and biological aspects
Stem Cell Research(2022)
摘要
•The multipotent mesenchymal stem cells (MSCs) are expected to activate apoptosis-related signaling pathways to restrict cancer cell proliferation and division.•The inherent tumor-tropic and migratory properties of MSCs make them act as targeted drug-delivery vehicles for isolated tumors and metastatic diseases.•MSCs are utilized for cell-based and intracellular suicide gene therapy, as well as carrying anti-cancer drug loaded nanoparticles, pre-drugs, and nanovesicles.
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关键词
Anticancer-drug delivery,Gene therapy,MSCs,Prostate cancer,Stem cell therapy
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