Uterine kallikrein and arterial bradykinin activities and uterine arterial proliferation in response to acute estradiol-17β exposure in ovariectomized ewes
Domestic Animal Endocrinology(2022)
Abstract
•Exposure to estradiol-17β in ovariectomized ewes tended to increase kallikrein specific activity in carcuncular tissue.•Uterine arteries from ovariectomized ewes treated with estradiol-17β for 24 and 48 h had greater sensitivity to bradykinin, via the bradykinin receptor 2, than uterine arteries from ewes with 0 or 12 h estradiol-17β exposure.
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Key words
Arterial function,Bradykinin,Estradiol-17β,Kallikrein,Sheep,Uterus
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