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Successful use of ivabradine in a 10-year-old patient with graft failure after heart transplantation

CARDIOLOGY IN THE YOUNG(2022)

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Abstract
We encountered a paediatric case of graft failure due to antibody-mediated rejection after heart transplantation in which ivabradine was effective. Inappropriate sinus tachycardia in denervated transplanted hearts is a good indication for ivabradine administration as beta-blockers have a limited efficacy. To our knowledge, this is the first report on the effectiveness of ivabradine in a paediatric heart transplant rejection case.
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Key words
Ivabradine,paediatrics,heart failure,heart transplantation,inappropriate sinus tachycardia,denervated hearts
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