The Effect of Growth Hormone Therapy on Cardiac Outcomes in Noonan Syndrome: Long Term Follow-up Results

Sirmen Kızılcan Çetin,Mehmet Gökhan Ramoğlu,Zeynep Şıklar,Elif Özsu,Zehra Aycan,Hasan Ercan Tutar,Merih Berberoğlu

Journal of clinical research in pediatric endocrinology（2022）

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摘要

In this cohort, there was no change in ECHO parameters on rGH and during follow-up. These results suggest that rGH is safe in NS patients with cardiac pathology under close follow-up.

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关键词

Noonan syndrome,Recombinant growth hormone therapy,hypertrophic cardiomyopathy,left ventricular dimension

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