The role of substance P on maintaining ligament homeostasis by inhibiting endochondral ossification during osteoarthritis progression.

Maya Tokumoto,Tomoyuki Nakasa,Yoshiko Shirakawa,Akinori Nekomoto,Yasunari Ikuta,Masakazu Ishikawa,Shigeru Miyaki,Nobuo Adachi

Connective tissue research（2023）

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摘要

SP plays an important role in maintaining ligament homeostasis by inhibiting endochondral ossification during OA progression. Targeting SP has therapeutic potential for preventing ligament degeneration.

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关键词

Ligament,degeneration,endochondral ossification,osteoarthritis,substance P

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