Differential health responses to climate change projections in three UK cities as measured by ambulance dispatch data

•Contemporary climate - health relationships for 3 major UK cities are studied and projected to 2060•Ambulance dispatch data is used as the health metric•Significant differences in health-related outcomes are observed for the different cities•Implications of future climate projections for cities within the same country are significant.•Predictive models of climate related ambulance dispatches need to be bespoke for individual cities.