HBx-Induced PLA2R Overexpression Mediates Podocyte Pyroptosis Through the ROS-NLRP3 Signaling Pathway

Moxuan Feng,Yani Yu,Yueqi Chen,Xiaoqian Yang,Baoshuang Li,Wei Jiang

SSRN Electronic Journal（2022）

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摘要

HBx-induced PLAR overexpression on the podocyte membrane can significantly upregulate the ROS-NLRP3 signaling pathway, thereby mediating podocyte pyroptosis.

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关键词

HBx,M-type phospholipase A2 receptor,nucleotide-binding oligomerization domain-like receptor protein 3,pyroptosis,reactive oxygen species

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