Highly Porous Composite Hydrogel Materials Based on β-Ca 3 (PO 4 ) 2 /Polyethylene Glycol Diacrylate

Perspektivnye Materialy(2022)

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Abstract
The possibility of obtaining highly porous hydrogel composite materials for biomedical applications based on tricalcium phosphate in a polyethylene glycol diacrylate matrix, aimed at repairing bone defects, has been studied. The effect of different content of inorganic filler particles exerted on the mechanical characteristics of highly porous hydrogel composites β-Ca 3 (PO 4 ) 2 /polyethylene glycol diacrylate has been studied. It is demonstrated that the preparation of highly porous composite materials with specified elastic properties is quite possible. The viscoelastic properties of the obtained materials are shown to depend on the preset pore size. Varying the tricalcium phosphate fraction in the highly porous hydrogel material makes it possible to control the relative stiffness of the composite.
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Key words
biomaterials,bone tissue regeneration,calcium phosphate,hydrogel,composite,macroporosity
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