Anion exchange and extraction chromatography tandem column isolation of zirconium-89 (89Zr) from cyclotron bombarded targets using an automated fluidic platform

•Zr(IV), Y(III), and Fe(III) Kd on LN resin across a range of HCl is reported.•Zr(IV) Kd on LN resin in acidic chloride and fluoride solutions are reported.•Zr(IV) Kd on LN resin across a range of oxalic acid is reported.•A tandem column 89Zr purification process is demonstrated using a fluidic system.•End-to-end 89Zr purification is demonstrated using seven cyclotron bombarded Y metal targets.•89Zr product quality determined by transchelation titrations with deferoxamine mesylate salt; results compared to literature values.