Peak O 2 -pulse predicts exercise training-induced changes in peak V̇O 2 in heart failure with preserved ejection fraction.

In patients with HFpEF, the easily measurable peak O -pulse seems to be a good indicator of the potential for improving peak V̇O through exercise training. While changes in submaximal exercise tolerance were independent of baseline peak O -pulse, patients with high O -pulse may need to use additional therapies to significantly increase peak V̇O .