Free radical scavenging synergism of fucoxanthin with lipophilic plant products

Fucoxanthin demonstrates potential bioactivity, gaining greater interest with many prospective applications. The fundamental activity of fucoxanthin is antioxidant. However, some findings also report the pro-oxidant potential of carotenoids in particular concentrations and environments. In many applications, fucoxanthin requires additional materials to improve bioavailability and stability, such as lipophilic plant products (LPP). Despite much-growing evidence, little is known how fucoxanthin interacts with LPP, which is susceptible to an oxidative reaction. We hypothesised that lower concentration of fucoxanthin exerts a synergistic effect in combination with LPP. The low molecular weight of LPP may exhibit greater activity than long-chain LPP, and so it does with the concentration of unsaturated moieties. We performed free radical-scavenging assay of fucoxanthin combined with some essential oils and edible oils. Chou-Talalay theorem was employed to depict the combination effect. The current study demonstrates a staple finding and constitutes theoretical viewpoints before further fucoxanthin's utilization with LPP.