Development and validation of a population-based anatomical colorectal model for radiation dosimetry in late effects studies of survivors of childhood cancer

Constance A. Owens,Bastien Rigaud,Ethan B. Ludmir,Aashish C. Gupta,Suman Shrestha,Arnold C. Paulino,Susan A. Smith,Christine B. Peterson,Stephen F. Kry,Choonsik Lee,Tara O. Henderson,Gregory T. Armstrong,Kristy K. Brock,Rebecca M. Howell

Radiotherapy and Oncology（2022）

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摘要

•Developed a colorectal model that includes anatomical variations of 103 individuals.•Colorectal model is age-scalable (0.1–18 years) across the pediatric age range.•Integrated colorectal model into the age-scalable in-house phantom.•The colorectal model can be integrated into any computational phantom.•The colorectal model will be used for dose reconstruction in late effects studies.

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关键词

Radiation therapy,Computational phantom,Childhood cancer,Late effects,Dose reconstruction,Radiation-related late effects

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