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Two new resin glycosides from Calystegia sepium (L.) R. Br. with potential antitumor activity

Huixian Liang,Jiayan Hu,Zhitong Li,Yongqin Yin

Journal of Molecular Structure（2022）

Cited 3|Views3
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Abstract
•Two new resin glycosides were isolated from Calystegia sepium (L.) R. Br. first.•Calystegins B was a rare hexasaccharide resin glycoside with macrolactone structure.•Calystegins B possess potential inhibitory effects on tumor microtubule proteins (ΔGb=-4.75 kcal/mol) and might be the lead compound of antitumor agent.
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Key words
Resin glycosides,Structural identification,Calyhedic acid A and B,Calystegia sepium (L.) R. Br.,Docking
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