CircTUBD1 Regulates Radiation-induced Liver Fibrosis Response via a circTUBD1/micro-203a-3p/Smad3 Positive Feedback Loop.

Hao Niu,Li Zhang,Biao Wang,Guang-Cong Zhang, Juan Liu,Zhi-Feng Wu,Shi-Suo Du,Zhao-Chong Zeng

JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY（2022）

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摘要

This study is the first to reveal the mechanism and role of circTUBD1 in RILF via a circTUBD1/micro-203a-3p/Smad3 feedback loop, which provides a novel therapeutic strategy for relieving the progression of RILF.

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关键词

Collagens,LX-2,Radiation-induced liver fibrosis,Three-dimensional,circRNA

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