Benzotriazole-oxadiazole hybrid Compounds: Synthesis, anticancer Activity, molecular docking and ADME profiling studies

Journal of Molecular Liquids(2022)

Cited 20|Views8
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Abstract
•Novel benzotriazole-oxadiazole derivatives was synthesized and characterized.•The synthesized compounds were investigated against PANC-1 cell line.•Compound 4d and 4b were found to be the most potent.•In silico molecular docking and ADME properties were calculated.
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Key words
Benzotriazole,Oxadiazole,Anticancer Activity,Molecular Docking,ADME
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