Plant Extract–Derived Nanomaterials for Wound Healing: a Mini Review

Purpose Wound infections and their side effects have become a problematic issue in clinical research. Nanomaterials like gold, silver, copper, and carbon prepared using plant source play vital roles as wound dressing material. They promote wound healing by aiding cellular proliferation and play chief role in skin repair and development. Nanoparticle-based wound dressing materials have the potential to reduce both the healing time of wounds and bioburden. This mini review focuses on recent findings in the field wound management and provides information about various nanomaterials in the wound healing process. Methods The author followed PRISMA guidelines to write this systematic review and obtained the information from various electronic databases. Results Wound healing has been extensively researched in an attempt to establish an “optimal” procedure that ensures rapid recovery while minimizing scarring and preserving function. Topical therapy using wound dressing is used in the conventional approach to manage wound, prevent infection, and promote good wound healing. Conclusion The rise of nanotechnology-based therapy has recently emerged as a potential therapy for treating wounds by accelerating wound healing. This review summarizes and discusses the current nanotechnology-based therapies that hold pivotal potential for wound healing and tissue regeneration, with a special emphasis on metal nanoparticles. Lay Summary Wounds are defined as sharp injuries to the skin tissue caused by external stimuli, in which the dermal layers are cut, punctured, or torn. Because of the unique physicochemical and biological features of nanoscale materials, nanotechnology has influenced several fields of biomedical engineering, including tissue engineering and regenerative medicine. Numerous studies showed nanotechnology and nanoscale-based techniques have emerged as possible platforms for wound healing applications. Nanotechnology provides a superior method for hastening the healing of acute and chronic wounds by promoting proper movement through the several stages of healing.