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Test comparison of seeds and skins extract of duku’s fruit ( Lansium domesticum Corr.) against the amount of melanin pigment of skin mencit ( Mus musculus ) to prevent premature aging of the skin

ADVANCES IN TRADITIONAL MEDICINE(2022)

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Abstract
Premature aging can occur due to excessive sun exposure which causes hyperpigmentation problems and causes brown or black patches on the skin. Duku ( Lansium domesticum Corr.) contains flavonoids and vitamin C compounds that are effective in protecting the skin from sun exposure. This study aims to see the benefits of the extract of the seeds and peel of duku fruit ( Lansium domesticum Corr.) On the amount of melanin pigment in the skin of mice ( Mus musculus ) as an anti-hyperpigmentation so that the dapjekal is a skin pen. Group P0 was a negative control, group P1 was exposed to sunlight for 20 days, group P2 mice were exposed to duku seed extract and then exposed to sunlight for 20 days, group P3 were exposed to duku peel and exposed to local sunlight for 20 days, P4 mice were exposed to sunlight 20 days, 21–30 days exposed to peel extract, and P5 mice exposed to sunlight 20 days, 21–30 days exposed to seed extract. The results showed that the P0 group had the amount of melanin pigment with an average of 7 grains, the P1 group: 68.4, P2 group: 26.6, P3 group: 29, P4 group: 7.2, and group P5 group: 12. The conclusion is that exposure to sunlight the amount of melanin pigment and offers the extract of the peel and seeds of duku fruit can reduce the amount of melanin pigment.
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Key words
Premature aging, Sunlight, Melanin pigment, Peel of duku's extract, Seeds of duku's extract
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